A highly selective synthesis of 3-hydroxy-2-methylpropionamide involving a one-pot tandem hydroformylation-hydrogenation sequence.

نویسندگان

  • Luis García
  • Carmen Claver
  • Montserrat Diéguez
  • Anna M Masdeu-Bultó
چکیده

3-Hydroxy-2-methylpropionamide, an important intermediate in the synthesis of methyl methacrylate, has been obtained with excellent conversion and high selectivity from acrylamide by a tandem hydroformylation-hydrogenation sequence catalysed by Rh/PPh3 and Raney Ni, respectively.

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عنوان ژورنال:
  • Chemical communications

دوره 2  شماره 

صفحات  -

تاریخ انتشار 2006